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Ideas, market perspectives and investment intelligence from the worlds of venture capital, healthcare and technology.

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Biotech Startup Valuation: rNPV in Practice

Valuation · September 1, 2026

Biotech Startup Valuation: rNPV in Practice

Valuing a biotech startup is unlike valuing almost any other kind of company. There's often no revenue, sometimes no product candidate that has reached the clinic, and the central question investors are trying to answer isn't "how fast is this growing" but "what is the […]

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Understanding 409A Valuations

Valuation · November 1, 2025

Understanding 409A Valuations

If you grant equity to employees, you need a 409A valuation. It's one of the more technical requirements founders face, but getting it wrong creates real tax exposure for your team and compliance risk for your company. Here's what founders need to understand. ## What […]

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Valuation Models for Medtech Startups

Valuation · December 1, 2024

Valuation Models for Medtech Startups

Medtech startups occupy a middle ground between software and therapeutics: they typically have shorter regulatory pathways than drugs, but longer development and reimbursement cycles than most software products. That hybrid profile means medtech founders need a valuation toolkit that blends traditional venture heuristics with milestone-based […]

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Valuing a Pre-Revenue Startup: Scorecard, Berkus and VC Method Compared

Valuation · November 1, 2024

Valuing a Pre-Revenue Startup: Scorecard, Berkus and VC Method Compared

Valuing a company with no revenue is one of the hardest conversations in early-stage fundraising. Without historical financials to anchor a discounted cash flow model, founders and investors instead lean on a handful of heuristic methods built specifically for pre-revenue and early-revenue companies. Three of […]

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Valuation · February 2, 2024

Startup Valuations: The Venture Capital Method

In the fast-paced and often unpredictable world of startups, venture capitalists rely on specialized methods to evaluate investment opportunities. Among these, the Venture Capital Method (VCM) of valuation is particularly notable for its unique fit in assessing early-stage companies. This method steps away from traditional valuation approaches, focusing instead on the future potential and the […]

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Valuation · November 24, 2023

Startup Valuation: An Overview of Methods and Practices

Valuation in venture capital is more than a mere financial assessment; it’s a critical decision-making tool that influences the trajectory of startups and investment strategies. This intricate process requires an understanding of various methodologies, each tailored to different stages of a startup’s growth and the unique dynamics of the venture capital market. This guide provides […]

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Valuation · March 16, 2023

Valuation Models for Biotechnology Startups

Posted: Mar 16, 2023 4:19 PM ET Biotechnology startups are becoming increasingly important to us as the world rushes towards a more digitalized and globalized future. With technology advancing faster than ever before, it is essential for companies to understand the potential value of their biotechnological investments in order to maximize their return on investment. […]

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